Endocrine, thyroid, molecular diagnosis, graves disease, diabetes. Hormone circulates in blood and acts at target organs where hormone receptor. Endocrine system drugs created by the njardarson group the university of arizona. Home explore pharmacology drugs acting on endocrine system. Similarly, fsh acts on sertoli cells to drive the secretion of a protein hormone, inhibin b, which then travels via the bloodstream to the pituitary gland to suppress. However, unlike neurotransmitters, which are released in close proximity to cells with their receptors, hormones are secreted. Hormones act on nearby tissues or are carried in the bloodstream to act on specific target organs and distant tissues. The two systems work together like a giant super system. Several synthetic steroids and hormonally active substances are able to affect the endocrine system. Chapter the endocrine system the endocrine system is made up of the hormone producing glands and tissues of the body.
Together with the nervous system, it is considered one the two long distance control systems of the body. Drugs acting on the endocrine system ali jaber, ph. Describe the common characteristics and functions of hormones. The endocrine system is a control system of ductless endocrine glands that secrete chemical messengers called hormones that circulate within the body via the bloodstream to affect distant organs. Data sources include ibm watson micromedex updated 4 may 2020, cerner multum updated 4 may 2020, wolters kluwer updated. Neurohormones synthesized in the hypothalamus reach the anterior pituitary adenohypophysis through a specialized portal vascular system and regulate synthesis and release of the 6 major peptide hormones of the anterior pituitary see figure the pituitary and its target organs. It does not include exocrine glands such as salivary glands, sweat glands and glands within the gastrointestinal tract subcategories.
These anterior pituitary hormones regulate peripheral endocrine glands the thyroid, adrenals, and gonads as well as growth and lactation. Find endocrine system course notes, answered questions, and endocrine system tutors 247. The endocrine system secretes these substances inside the body to regulate metabolism, fertility, the fightorflight response, and cell growth, among other responsibilities. Objectives discuss the physiologic effects of insulin on carbohydrate, lipid, and protein metabolism, and identify those body cellstissues that most depend on insulin for providing glucose as the main metabolic fuel. A plethora of hormones regulate many of the bodys functions, including growth and development, metabolism, electrolyte. All of these glands coordinate with each other in order to regulate various life processes. Objectives discuss the physiologic effects of insulin on carbohydrate, lipid, and protein metabolism, and identify those body cellstissues that most depend on insulin. They tend to have very long halflives of days to weeks, metabolism is not. Questions on diabetes type 1 and 2, adh insufficiency, adrenal disorders, thyroid disorders, reproductive treatments, and more.
To this day we have a serious lack of data in regards to this topic despite the fact that opioids both endogenous and exogenousevidently affect the endocrine system katz and mazer, 2009. Neuroendocrine system gland found in the sella turcica of the brain. There are many drugs that can be used to influence the endocrine system. Of course, you want relief from your anxiety and you can get that since anxiety is incredibly treatable but what you do not want to do is stop this system from occurring in general, because its an extremely important system for.
Hypothalamic hormones regulate the release of anterior pituitary hormones. Erythropoietin is produced when oxygen levels in the blood are low. Somatostatin is released by delta cells and acts as an inhibitor of gh, insulin and glucagon. All the endocrine agents listed below are peptides, except for prolactininhibiting hormone. Evaluate changes in weight, particularly increase in weight in the adult and decrease in weight in the child. Insulin lispro humalog, insulin aspart novolog, insulin glulisin apidra 0.
Overviewoverview endocrine system composed of hormonereleasing organs such as the. In such cases, the substance may possess inherent hormonal activity and therefore act rather specifically on a particular target organ of the endocrine system. The nervous system acts by using a rapid, short lived response while the endocrine system produces a slow, longer response. Pharmacology of the endocrine system 2 in clinical practice, hormones and hormonelike drugs, are mainly used for. If so, share your ppt presentation slides online with. Datye, md, is a pgy3 resident in pediatrics, vanderbilt university school of medicine. This category has the following 18 subcategories, out of 18 total. Drugs used to treat endocrine disorders pharmacology. The endocrine system maintenance of internal homeostasis through the secretion of hormones endocrine glands make and release these endogenous substances to regulate.
Endocrine drugs, hormones andendocrine drugs, hormones and related compoundsrelated compounds 2. It acts in bone marrow to stimulate the production of mature red blood cells and to maintain. Drugs acting on the endocrine system flashcards quizlet. Drugs affecting the endocrine system pharmacology thyroid. Review common endocrine conditions that often present in the newborn and perinatal period. Insulin lispro humalog rapid acting within 15 min regular insulin humulin short, subq, iv only insulin that can be given iv insulin isophane nph intermediate. The pituitary serves as the master gland, controlling the secretions of all other glands. Adrenal hormones glucocorticoids mechanism of action. Oxytocin and vasopressin are produced in the posterior pituitary an outgrowth of the hypothalamus where they are released into general circulation. The presence of functioning tumours in more than one endocrine gland, commonly the pancreatic islets and parathyroid glands, which may be associated with zollingerellison syndrome. Drugs acting on the endocrine system thyroid glands.
Here is a rundown of the endocrines glands that form this system and their functions. The endocrine system acts through the release generally into the blood of chemical agents and is vital to the proper development and function of organisms. Endocrine glands are ductless glands of the endocrine system that secrete their products. Pth acts on bone, the kidneys, and the gi tract to increase calcium reabsorption and phosphate excretion. Treatment and management of common endocrine disorders open. Endocrinology relationships between the endocrine and. The exocrine system works similarly, but secretes substances outside the body.
Endocrine glands are the glands of endocrine system which normally secrete special products called hormones directly into the blood 14. Course hero has thousands of endocrine system study resources to help you. Overview of the endocrine system endocrine and metabolic. In addition, pth stimulates the conversion of vitamin. Pharmacology of the endocrine system proprofs quiz. Both the nervous system and endocrine system perform this function in higher animals. Adrenal hormones glucocorticoids mechanism of action, therapeutic uses and adverse effects. This drug combats acromegaly by acting as somatostain, a growth hormone release inhibiting factor.
The glands of the endocrine system secrete hormones to regulate normal body functions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It does not include exocrine glands such as salivary glands, sweat glands and glands within the gastrointestinal tract. Treatment and management of common endocrine disorders. They do not have ducts and hence they are called as ductless glands. The endocrine system consists of a series of glands that produce chemical substances known as hormones. Chapter 48 nursing assessment endocrine system susan c. Drugs acting on the endocrine system by kathrine kaye. The endocrine system consists of a collection of glands that regulate a number of vital functions of our body. Ppt drugs acting on the endocrine system powerpoint. The endocrine system and control this entire system is not something you can or want to specifically control. Module 6 the nervous system and the endocrine system. Chemicals secreted by the glands of this system have effects on numerous organs of multiple systems and control or regulate various mechanisms of every other body system the major endocrine glands.
Chemicals secreted by the glands of this system have effects on numerous organs of multiple systems and control or regulate various mechanisms of every other body system. The endocrine system works with the nervous system to regulate and integrate the processes of the body such as growth, development, reproduction, response to stress, and change of food into energy and body tissue. What drugs can cause complications endocrine exocrine. Inhibits osteoclast activity, reduces bone reabsorption. Medications affecting the endocrine system part 1diabetes mellitus objectives. Evaluate reflexes and neuromuscular response to stimuli. Testing the functional integration of an endocrine system diagnostic. The way the endocrine system works is by releasing chemical messengers called hormones into the blood. Currently there are 3 recognized classes of injectable antihyperglycemics. Landis nobody can go back and start a new beginning, but anyone can start today and make a new ending.
Organs which are affected by a hormone are called target organs. Communicating within the body 63 the evolutionary foundations of the nervous system the complexities of the nervous system can be better understood if we take the course of evolution into consideration. Apr 29, 2008 comparison of insulin peak action 1020 hrs 48 hrs ultralente long acting 68 hrs to 12 hrs 1. Drugs affecting the endocrine system lange smart charts. Consider the thyroid gland, an important part of this system. Drugs acting on the endocrine system hypothalamic and pituitary agents pharmacokinetics for the most part, these drugs are absorbed slowly when given intramuscularly im, subcutaneously, or in depot form. By mary green the endocrine system consists of a collection of glands that regulate a number of vital functions of our body. Medications affecting the endocrine syst authorstream. Like neurotransmitters, hormones are chemical messengers that must bind to a receptor in order to send their signal. In fact the hypothalamus, a part of the nervous system, and the pituitary gland, a.
Sweat glands, saliva, and mammary glands are all parts of the exocrine system. Endocrine glands send chemical signal molecules around the body to communicate information. The impact of opioids on the endocrine system request pdf. More endocrine system quizzes learn about endocrine system quiz. System nursing 3703 pharmacology by linda self hypothalamic, pituitary, parathyroid, and adrenal hormones hypothalamus secretes releasing hormones affecting both the anterior and posterior pituitary posterior pituitary secretes adh and oxytocinadh conserves water, oxytocin functions in childbirth and lactation anterior pituitary hormones and target tissues 1. When an electrical signal in the form of an action potential arrives at the synaptic terminal, they diffuse across the synaptic. Endocrine system is a series of organs and glands in your body that secret chemical messengers called hormones in to your blood stream. Effects of drugs on the endocrine system springerlink. A plethora of hormones regulate many of the bodys functions, including growth and development, metabolism, electrolyte balances, and reproduction.